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| Product Name | Recombinant Mouse Transcription factor GATA-4 (GATA4) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 49.6kDa. Full Length: 1-441aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Mus musculus (Mouse). Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | GATA-binding factor 4; Gata-4 |
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| Gene, Accession, CAS # | GATA4, UniProt: Q08369 |
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| Catalog # | RPC21355 |
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| Order / More Info | Recombinant Mouse Transcription factor GATA-4 (GATA4) from BIOMATIK |
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| Product Specific References | n/a |
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