| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (aa 602-681) |
|---|
| Clone | 2G4E12 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | ascites |
|---|
| Size | 0.1 mL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),ELISA |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | DDR1: discoidin domain receptor tyrosine kinase 1. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants.Synonyms: CAK, DDR, NEP, PTK3, RTK6, TRKE, CD167 |
|---|
| Immunogen | Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli. |
|---|
| Other Names | CG11573|CG13984|CG13985|CG33531|CG9488|CG9490|CT33540|DDR|Dmel\\CG33531|Dmel_CG13984|6030432F18|AI323681|CD167a|Cak|Nep|PTK3A|CAK|CD167|EDDR1|HGK2|MCK10|NEP|NTRK4|PTK3|RTK6|TRKE|Drd1|PTK3D |
|---|
| Gene, Accession # | Gene ID: 780 |
|---|
| Catalog # | ABIN965982 |
|---|
| Price | |
|---|
| Order / More Info | Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (aa 602-681) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 10783152, 15799117, 12477932, 11133186 |
|---|
| 产品资料 |
|
|