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| Product Name | Protein S, Human |
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| Description | Purity ≥95% by SDS-PAGE. Human Protein S is isolated from fresh frozen plasma by a combination of conventional methods and immunoaffinity chromatography as described by Jenny, et al. Purity is determined by SDS-PAGE analysis. Domain Structure of Protein S: GLA Region: contains g-carboxyglutamic acid residues, EGF Region: contains sequences homologous to human epidermal growth factor, TSR = Thrombin sensitive region, Region of unknown function which replaces the catalytic triad found in vitamin K-dependent serine proteases. Protein S is a single chain vitamin K-dependent protein which is thought to function in both the coagulation and complement cascades (1,2). Approximately 60% of protein S circulating in plasma is complexed to C4b binding protein (C4BP). It has been suggested that g-carboxyglutamic acid (gla) dependent binding of protein S to negatively charged phospholipids may function to concentrate C4BP at cell surfaces following injury. In the coagulation system, Protein S functi |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9107-75 |
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| Order / More Info | Protein S, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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