| 产品详情 |
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| Antigenic Specificity | PI3-kinase p85 alpha/gamma (pY467/199) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-PI3-kinase p85 alpha/gamma (Tyr467/199) Antibody detects endogenous levels of PI3-kinase p85 alpha/gamma only when phosphorylated at Tyrosine 467/199. PIK3R1 is a regulatory subunit of phosphoinositide-3-kinase. Mediates binding to a subset of tyrosine-phosphorylated proteins through its SH2 domain. Acts as an adapter, mediating the association of the p110 catalytic unit of the alpha, beta and delta enzymes to the plasma membrane, where p110 phosphorylates inositol lipids. May play an additional role in the regulation of the actin cytoskeleton. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. |
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| Immunogen | n/a |
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| Other Names | GRB1; P85A; PI3-kinase p85-alpha subunit; PI3K; PI3K p85-alpha; Phosphatidylinositol 3-kinase regulatory alpha subunit; PtdIns-3-kinase p85-alpha; P55G; PI3-kinase p85-gamma subunit; PI3K p85-gamma; Phosphatidylinositol 3-kinase regulatory gamma subunit; PtdIns-3-kinase p85-gamma; p55PIK |
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| Gene, Accession # | SwissProt: P27986, Q92569 |
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| Catalog # | abx011344 |
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| Price | |
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| Order / More Info | PI3-kinase p85 alpha/gamma (pY467/199) Antibody from ABBEXA |
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| Product Specific References | n/a |
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