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Product Name | Recombinant Human ACK1 / TNK2 Protein (GST tag) |
Description | MW: 119,349 Da. Purity >90 % as determined by SDS-PAGE. Background: ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell type s. This downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. The ACK1 protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation |
Size | 0.02 mg, 0.05 mg |
Concentration | n/a |
Applications | The recombinant human ACK1/GST chimera consists of 592 amino acids and predicts a molecular mass of 68 kDa. It migrates as an approximately 62 kDa band in SDS-PAGE under reducing conditions. |
Other Names | [TNK2, ACK, ACK1, FLJ44758, FLJ45547, p21cdc42Hs] |
Gene, Accession, CAS # | ACK1 / TNK2, Gene ID: 10188, Accession: NP_005772.3 |
Catalog # | MBS2545167 |
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Order / More Info | Recombinant Human ACK1 / TNK2 Protein (GST tag) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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