| 产品详情 |
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| Antigenic Specificity | Kelch-Like 13 (Drosophila) (KLHL13) |
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| Clone | 8D1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KLHL13 (kelch-like 13), also known as BKLHD2 (BTB and kelch domain-containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate- specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase. |
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| Immunogen | Purified recombinant fragment of human KLHL13 expressed in E. coli. |
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| Other Names | 1200009K10Rik|AI451128|Bklhd2|D130072F20Rik|mKIAA1309|BKLHD2 |
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| Gene, Accession # | Gene ID: 90293 |
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| Catalog # | ABIN969245 |
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| Price | |
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| Order / More Info | Kelch-Like 13 (Drosophila) (KLHL13) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15342556 |
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