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Antigenic Specificity | ADAMTS-Like 1 (ADAMTSL1) |
Clone | 1B2-8-2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | n/a |
Applications | Immunoassay (IA),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody 1B2-8-2 reacts with Punctin-1 (ADAMTSL-1). Punctin-1 is a secreted molecule resembling members of the family of proteases designated ADAMTS (a disintegrin-like and metalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes that consist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (which provide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including 4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into the cell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2 (ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to have important functions in the extracellular matrix. Monoclonal antibody 1B2-8-2 recognizes the first thrombospondin repeat near the N-terminal and reacts with molecular species of 55 kDa or a doublet of 55 k Da and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained. |
Immunogen | n/a |
Other Names | ADAMTSL1|ADAMTSL-1|ADAMTSR1|C9orf94|PUNCTIN|5930437A14Rik|6720426B09Rik |
Gene, Accession # | Gene ID: 92949 |
Catalog # | ABIN2192028 |
Price | |
Order / More Info | ADAMTS-Like 1 (ADAMTSL1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 11805097 |