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| Product Name | PNP, 1-289aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 34.2 kDa (309aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2'-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficienc |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Purine nucleoside phosphorylase; NP; Inosine phosphorylase; PRO1837; PuNP] |
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| Gene, Accession, CAS # | PNP, Gene ID: 4860, Accession: NP_000261 |
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| Catalog # | MBS203884 |
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| Order / More Info | PNP, 1-289aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Dautant A., et al. (2010) J Biol Chem. 285 (38):29502-10.; Balakrishnan K., et al. (2010) Blood. 116 (6):886-92.; |
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