产品名称 Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (AA 687-979) protein (His tag) from ANTIBODIES-ONLINE GmbH
产品货号 ABIN2115413
产品价格 现货询价,电话:010-67529703
产品规格 500 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameProtein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (AA 687-979) protein (His tag)
DescriptionReceptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Synonyms: Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512
Size500 µg
Concentrationn/a
Applicationsn/a
Other NamesIA-2|IA-2/PTP|IA2|ICA512|R-PTP-N|mIA-A|mKIAA4064|Ia-2
Gene, Accession, CAS #Gene ID: 5798
Catalog #ABIN2115413
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Order / More InfoProtein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (AA 687-979) protein (His tag) from ANTIBODIES-ONLINE GmbH
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