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Antigenic Specificity | Multiple PDZ Domain Protein (MPDZ) (aa 1450-1500) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Function: Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.Subcellular location: Cell membrane, Peripheral membrane protein, Cytoplasmic side. Apical cell membrane, Peripheral membrane protein, Cytoplasmic side. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell junction, synapse. Cell junction, tight junction. Cell junction, synapse. Cell junction, synapse, synaptosome. Note: Associated with membranes. Colocalizes with HTR2C on the apical membrane of epithelial choroid plexus cells. Highly enriched in postsynaptic densities (PSD). Localized to punctae on dendrites of hippocampal neurons and colocalizes with the synaptic marker DLG4. Localized mainly in the Schmidt-Lanterman incisures of myelinating Schwann cells. In the retina, localizes to the sub-apical region adjacent to the adherens junction complex at the outer limiting membrane. Enriched at the tight junctions of epithelial cells. Association to the tight junctions depends on CXADR.Tissue specificity: Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Also known as: MPDZ, MUPP1, Multi PDZ domain protein 1, Multi-PDZ domain protein 1. |
Immunogen | A synthetic peptide from aa region 1450-1500 of human MUPP1 conjugated to blue carrier protein was used as the antigen. |
Other Names | HYC2|MUPP1|AI225843|B930003D11Rik |
Gene, Accession # | Gene ID: 8777 |
Catalog # | ABIN350501 |
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Order / More Info | Multiple PDZ Domain Protein (MPDZ) (aa 1450-1500) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 18669648, 15164053, 11000240, 14702039, 9537516 |
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