产品名称 Lovastatin from TOCRIS BIOSCIENCE
产品货号 1530/50
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 TOCRIS BIOSCIENCE
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Product NameLovastatin
DescriptionPotent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Indirectly inhibits Rho-GTPase activity by depleting intracellular pool of isoprene residues. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro. Inactive lactam prodrug of lovastatin hydroxy acid, naturally bioactivated in vivo following oral administration. Purity 98%. MW (observed): 404.54
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names(2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate. Mevinolin
Gene, Accession, CAS #CAS: 75330-75-5
Catalog #1530/50
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Order / More InfoLovastatin from TOCRIS BIOSCIENCE
Product Specific ReferencesPubMed: 22202492, 22710979, 23892605, 24489942, 24762141, 25945415, 26501302, 27270401
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