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| Product Name | Recombinant Human Kininogen-1 protein |
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| Description | 390-639aa; Partial. MW: 31.9kD. Purity >90% as determined by SDS-PAGE. 1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle con |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Alpha-2-thiol proteinase inhibitor; Fitzgerald factor High molecular weight kininogen; HMWK; Williams-Fitzgerald-Flaujeac factor] |
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| Gene, Accession, CAS # | KNG1, Gene ID: 3827, Accession: NP_000884.1 |
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| Catalog # | MBS961660 |
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| Order / More Info | Recombinant Human Kininogen-1 protein from MYBIOSOURCE INC. |
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| Product Specific References | Isolation of a human cDNA for alpha 2-thiol proteinase inhibitor and its identity with low molecular weight kininogen.Ohkubo I., Kurachi K., Takasawa T., Shiokawa H., Sasaki M.Biochemistry 23:5691-5697(1984) Cloning and sequence analysis of cDNAs for human high molecular weight and low molecular weight prekininogens. Primary structures of two human prekininogens.Takagaki Y., Kitamura N., Nakanishi S.J. Biol. Chem. 260:8601-8609(1985) Complete sequencing and characterization of 21,243 full-length |
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