| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Kruppel-Like Factor 8 (KLF8) (aa 1-18), (N-Term) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | KLF8(Krueppel-like factor 8) is a protein that in humans is encoded by the KLF8 gene. It is also named as ZNF741, or BKLF3. Kruppel-like factor proteins, including KLF8, all contain a characteristic C-terminal DNA-binding domain containing 3 Kruppel-like zinc fingers, and they all recognize CACCC and GC boxes present in promoters and enhancers. The International Radiation Hybrid Mapping Consortium mapped the KLF8 gene to the X chromosome(WI-18614). Suske et al.(2005) stated that the human KLF8 gene maps to chromosome Xp11.21, and the mouse Klf8 gene to chromosome XF3. van Vliet et al.(2000) identified a cDNA encoding KLF8, also called ZNF741. Expression of KLF8 or only its zinc fingers showed that the fingers could bind to a CACCC box. Sequence analysis predicted that the 359-amino acid protein contains a nuclear localization signal upstream of the zinc fingers, a valine-rich hydrophobic stretch, and a pro-val-asp-leu-ser(PVDLS) motif. Yeast 2-hybrid and GST pull-down analysis demonstrated that CTBP2 interacts with KLF8 through the PVDLS motif. |
|---|
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human KLF8(1-18aa MVDMDKLINNLEVQLNSE). |
|---|
| Other Names | klf8|BKLF3|ZNF741|A830097P10Rik|ZNF74|Klf8-ps1|RGD1565831 |
|---|
| Gene, Accession # | Gene ID: 11279 |
|---|
| Catalog # | ABIN1673369 |
|---|
| Price | |
|---|
| Order / More Info | Kruppel-Like Factor 8 (KLF8) (aa 1-18), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 15820306, 10756197, 11836360 |
|---|
| 产品资料 |
|
|