| 产品详情 |
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| Antigenic Specificity | AKT1S1 |
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| Clone | AKT1S1-3 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-AKT1S1 Recombinant Antibody (AKT1S1-3). This product is a mouse antibody that recognizes AKT1S1. The antibody AKT1S1-3 can be used for immunoassay techniques such as: IP, WB. AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein when phosphorylated. Akt1s1, which they called Pras40, from rat hepatoma cells. By EST database analysis, they identified mouse and human PRAS40. The deduced 256-amino acid human protein contains 2 N-terminal proline-rich regions and a C-terminal AKT phosphorylation site, thr246, that is conserved in rat and mouse. mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, |
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| Immunogen | Fusion protein from Human PRAS40 (N terminal) |
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| Other Names | AKT1 Substrate 1 (Proline-Rich); 40 KDa Proline-Rich AKT Substrate; PRAS40; Proline-Rich Akt Substrate; 40 KDa; Lobe |
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| Gene, Accession # | Gene ID: 84335, UniProt: Q96B36 |
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| Catalog # | CBMAB-0045CQ |
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| Price | |
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| Order / More Info | AKT1S1 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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