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| Product Name | Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (AA 65-196) protein (His tag) |
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| Description | Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) is a single-pass type I membrane protein and specifically expressed in T- and B-cells. SIT1 interacts with PTPN11/SHP2, GRB2 and CSK, when it is phosphorylated. SIT1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cell. In addition, SIT1 is involved in positive selection of T-cells.Alternative Names: Signaling Threshold-Regulating Transmembrane Adapter 1, SHP2-Interacting Transmembrane Adapter Protein, Suppression-Inducing Transmembrane Adapter 1, gp30/40, SIT1, SIT |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIT1|RP11-331F9.5|SIT|SIT-R|Sit |
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| Gene, Accession, CAS # | Gene ID: 27240 |
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| Catalog # | ABIN1097543 |
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| Order / More Info | Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (AA 65-196) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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