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Product Name | IL-6 protein |
Description | Human Interleukin-6 Interleukin 6 (IL-6) is a multifunctional protein that plays important roles in host defense, acute phase reactions, immune responses, and hematopoiesis. According to the type of biological responses being studied, IL-6 was previously named interferon- beta 2, 26-kDa protein, B cell stimulatory factor-2 (BSF-2), hybridoma/plasmacytoma growth factor, hepatocyte stimulating factor, cytotoxic T cell differentiation factor, and macrophage-granulocyte inducing factor 2A (MGI-2A). The IL-6 designation was adopted after these variously named proteins were found to be identical on the basis of their amino acid and/or nucleotide sequences. IL-6 is expressed by a variety of normal and transformed cells including T cells, B cells, monocytes/macrophages, fibroblasts, hepatocytes, keratinocytes, astrocytes, vascular endothelial cells, and various tumor cells. The production of IL-6 is upregulated by numerous signals including mitogenic or antigenic stimulation, LPS, calcium ionophore, IL-1, IL-2, IFN, TNF, PDGF, and viruses. IL-6 expression in monocytes is inhibited by IL-4 and IL-13. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Il-6|ILg6|Ifnb2|BSF2|HGF|HSF|IFNB2|IL-6|CHIL-6|il6 |
Gene, Accession, CAS # | Gene ID: 3569 |
Catalog # | ABIN1540352 |
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Order / More Info | IL-6 protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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