| 产品详情 |
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| Product Name | Allograft Inflammatory Factor 1 (AIF1) protein (His tag) |
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| Description | Human AIF1 protein shares 98 % homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor malignancy in humans Synonyms: AIF-1, Allograft inflammatory factor 1, Em: AF129756.17, G1, IBA1, Ionized calcium-binding adapter molecule 1, IRT-1, Protein G1, AIF1 |
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| Size | 2 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Other Names | fa04b11|wu:fa04b11|AIF1|aif1|AIF-1|IBA1|IRT-1|IRT1|Bart1|iba1|mrf-1|AI607846|D17H6S50E|G1|Iba1|AIF|AIF1L |
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| Gene, Accession, CAS # | Gene ID: 199 |
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| Catalog # | ABIN805148 |
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| Order / More Info | Allograft Inflammatory Factor 1 (AIF1) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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