| 产品详情 |
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| Antigenic Specificity | ARRB2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | IHC-P, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to ARRB2. ARRB2 (arrestin beta 2), also known as beta arrestin-2, BARR2, ARB2, DKFZp686L0365, arrestin 3, is an intracellularprotein that in humans is encoded by the ARRB2 gene. Members of arrestin/beta arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. beta arrestins were originally discovered in the context of heterotrimeric G protein-coupled receptor desensitization, but they also function in internalization and signaling of these receptors. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human ARRB2, different from the related rat and mouse sequences by two amino acids |
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| Other Names | HSPB2 |
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| Gene, Accession # | n/a |
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| Catalog # | orb11647 |
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| Price | |
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| Order / More Info | ARRB2 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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