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Product Name | Interleukin-6 Receptor (IL6R) (AA 20-365) (Active) protein |
Description | Interleukin-6 Receptor Alpha, also known as IL-6RA, IL-6R1 and CD126, belongs to the type I cytokine receptor family. It is mainly expressed on T cells, fibroblasts and macrophages. IL-6RA couples with gp130 to form the IL-6 receptor, IL-6RA binds specifically to IL-6 and depends on gp130 to transmit signals. IL-6RA dysfunction has been correlated with the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Soluble IL-6RA, which consists of only the extracellular domain of IL-6RA, acts as an agonist of IL-6 activity.Synonyms: IL-6RA, IL-6R1, CD126 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | IL6R|il-6ra|CD126|IL-6R-1|IL-6RA|IL6Q|IL6RA|IL6RQ|gp80|IL6R1|Il6ra|IL-6Ralpha|IL-6R|Il6r |
Gene, Accession, CAS # | Gene ID: 3570 |
Catalog # | ABIN2018148 |
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Order / More Info | Interleukin-6 Receptor (IL6R) (AA 20-365) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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