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Product Name | Recombinant Human C-X-C motif chemokine 11 protein (CXCL11) (Active) |
Description | Purity > 95% as determined by SDS-PAGE. MW: 16.9kDa. Full Length: 1-155aa. tag-Free. Homo sapiens (Human). Human Interleukin-36 Receptor Antagonist (IL-36RN) is a secreted protein which belongs to the Interleukin 1 cytokine family (IL-1 family). IL-36RN is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. IL-36RN is also detected in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin. IL-36RN is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to Interleukin 1 family member 9 (IL1F9). Dysregulated expression of novel agonistic and antagonistic IL-1 family member ligands can promote cutaneous inflammation, revealing potential novel targets for the treatment of inflammatory skin disorders. Human and mouse IL-36RN share 90% sequence identity. |
Size | n/a |
Concentration | n/a |
Applications | RUO |
Other Names | Interleukin-36 Receptor Antagonist Protein; FIL1 Delta; IL-1-Related Protein 3; IL-1RP3; Interleukin-1 HY1; IL-1HY1; Interleukin-1 Delta; IL-1 Delta; Interleukin-1 Family Member 5; IL-1F5; Interleukin-1 Receptor Antagonist Homolog 1; IL-1ra Homolog 1; Interleukin-1-Like Protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3 |
Gene, Accession, CAS # | IL36RN, UniProt: Q9UBH0 |
Catalog # | RPC26887 |
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Order / More Info | Recombinant Human C-X-C motif chemokine 11 protein (CXCL11) (Active) from BIOMATIK |
Product Specific References | n/a |
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