产品名称 Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 4 from MYBIOSOURCE INC.
产品货号 MBS951626
产品价格 现货询价,电话:010-67529703
产品规格 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli)
产品品牌 MYBIOSOURCE INC.
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Product NameRecombinant Mouse Dual specificity mitogen-activated protein kinase kinase 4
Description2-397aa; Full Length. MW: 60kD. Purity >90% as determined by SDS-PAGE. Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MK
Size0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli)
Concentrationn/a
Applicationsn/a
Other Names[C-JUN N-terminal kinase kinase 1; JNK kinase 1; JNKK 1; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1]
Gene, Accession, CAS #Map2k4, Gene ID: 26398, Accession: NP_033183.1
Catalog #MBS951626
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Order / More InfoRecombinant Mouse Dual specificity mitogen-activated protein kinase kinase 4 from MYBIOSOURCE INC.
Product Specific ReferencesRole of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun.Sanchez I., Hughes R.T., Mayer B.J., Yee K., Woodgett J.R., Avruch J., Kyriakis J.M., Zon L.I.Nature 372:794-798(1994) Zon L.I.SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.Swat W., Fujikawa K., Ganiatsas S., Yang D., Xavier R.J., Harris N.L., Davidson L., Ferrini R., Davis R.J., Labow M.A., Flavell R.A., Zon L.I., Alt F.W.Immunity
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