| 产品详情 |
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| Product Name | Recombinant Human Hepatitis B virus X-interacting protein (HBXIP) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 36.6kDa. Full Length: 1-91aa. N-terminal GST-tagged. Homo sapiens (Human). As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Hepatitis B virus X-interacting protein |
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| Gene, Accession, CAS # | HBXIP, UniProt: O43504 |
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| Catalog # | RPC21438 |
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| Order / More Info | Recombinant Human Hepatitis B virus X-interacting protein (HBXIP) from BIOMATIK |
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| Product Specific References | n/a |
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