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| Product Name | Recombinant Human Hemojuvelin / HFE2 Protein (His tag) |
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| Description | MW: 21,463 Da. Purity >95 % as determined by SDS-PAGE. Background: Hemojuvelin, also known as HFE2, is a membrane-bound and soluble protein which belongs to the repulsive guidance molecule (RGM) family. It is known that RGMs function through Neogenin, a homologue of the Netrin receptor deleted in colon cancer. In mammals, RGM family consists of three glycoproteins which have discrete expression patterns and functions (RGM-A, RGM-B, and RGM-C). Hemojuvelin is expressed in adult and fetal liver, h |
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| Size | 0.05 mg, 0.1 mg |
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| Concentration | n/a |
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| Applications | The secreted recombinant human HFE2 consists of 374 amino acids and predicts a molecular mass of 40 kDa. As a result of intracellular cleavage, the apparent molecular mass of the protein is approximately 20, 34 and 44 KDa in SDS-PAGE under reducing conditions, corresponding to the N-terminal, C-terminal portions and the full-length respectively. |
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| Other Names | [HFE2A, HJV, JH, RGMC] |
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| Gene, Accession, CAS # | HFE2, Gene ID: 148738, Accession: NP_001303696.1 |
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| Catalog # | MBS2546275 |
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| Price | |
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| Order / More Info | Recombinant Human Hemojuvelin / HFE2 Protein (His tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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