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| Product Name | Recombinant Human U1 small nuclear ribonucleoprotein A |
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| Description | 8-278aa; Partial. MW: 57.4kD. Purity >90% as determined by SDS-PAGE. Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds st loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylati |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [U1 small nuclear ribonucleoprotein A; U1 small nuclear ribonucleoprotein A; U1 small nuclear ribonucleoprotein A; small nuclear ribonucleoprotein polypeptide A] |
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| Gene, Accession, CAS # | SNRPA, Gene ID: 6626, Accession: NP_004587.1 |
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| Catalog # | MBS717096 |
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| Order / More Info | Recombinant Human U1 small nuclear ribonucleoprotein A from MYBIOSOURCE INC. |
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| Product Specific References | Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein.Nelissen R.L.H., Sillekens P.T.G., Beijer R.P., Geurts van Kessel A.H.M., van Venrooij W.J.Gene 102:189-196(1991) cDNA cloning of the human U1 snRNA-associated A proteinextensive homology between U1 and U2 snRNP-specific proteins.Sillekens P.T.G., Habets W.J., Beijer R.P., van Venrooij W.J.EMBO J. 6:3841-3848(1987) Bienvenut W.V.Submitted (JAN-2004) to UniProtKBThe snRNP-free |
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