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Product Name | PFI-3 |
Description | MW: 321.37. Purity ≥98% by HPLC. Background: PFI-3 is a potent and selective polybromo 1 (PB1) and SMARCA4 (SWI/SNF related, Matrix associated, Actin dependent Regulator of Chromatin, subfamily A, member 4) inhibitor (Kd values are 48 and 89 nM respectively). SMARCA4, also known as BRG1 (Brahma-Related Gene1), is part of the SWI/SNF (SWItch/Sucrose Non-Fermentable) family of proteins. Loss of function of SMARCA4 and components of SWI/SNF has been linked to cancer development suggesting a tumo |
Size | 5 mg, 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one] |
Gene, Accession, CAS # | [PFI-3] |
Catalog # | MBS843156 |
Price | |
Order / More Info | PFI-3 from MYBIOSOURCE INC. |
Product Specific References | n/a |
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