| 产品详情 |
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| Antigenic Specificity | Complement Component Receptor 1 (CD35) (CR1) |
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| Clone | 31R |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Flow Cytometry (FACS),Immunoprecipitation (IP),Immunoassay (IA),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Immunohistochemistry (Frozen Sections) (IHC (fro)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD35 (CR1) is a type 1 membrane glycoprotein participating in clearance of immune complexes, regulation of autologous complement activation on cell surfaces, and complement-dependent cellular cytotoxicity mediated by leukocytes. CD35 inhibits complement activation by two distinct mechanisms. CD35 is a cofactor for factor I cleavage of C3b, iC3b and C4b. Furthermore CD35 mediates decay- dissociation of C3 and C5 convertases. CD35 is found on erythrocytes, neutrophils, monocytes and dendritic cells. There are four allotypic variants of CR35 (CR1) with different molecular masses: 190 kDa (CR-1A), 220 kDa (CR1-B), 160 kDa (CR1-C) and 250 kDa (CR1-D). The monoclonal antibody 31R binds a single epitope of CR1. |
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| Immunogen | n/a |
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| Other Names | C3BR|C4BR|CD35|KN|C3DR|CD21|Cr-1|Cr-2|Cr1 |
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| Gene, Accession # | Gene ID: 1378 |
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| Catalog # | ABIN2191985 |
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| Price | |
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| Order / More Info | Complement Component Receptor 1 (CD35) (CR1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 8796479 |
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