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| Product Name | Mouse IL-6 Receptor Recombinant (IL-6R) |
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| Description | Purity >97%, as determined by SDS-PAGE and HPLC. The effects of IL-6 are mediated by a functional IL- 6 receptor (IL-6R), which consists in a heterodimer formed by an IL-6-binding α chain (IL-6Rα) and a signal- transducing subunit, gp130 or IL-6Rβ. Binding of IL-6 to the IL-6Rα induces homodimerization of two gp130 molecules, leading to intracellular signals. |
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| Size | 0.01 mg, 0.05 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mouse CD126 Recombinant (IL6 Receptor) ; cd-126 IL6R; CD126; IL-6R-1; IL-6R-alpha; IL6RA; MGC104991; IL6 Receptor] |
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| Gene, Accession, CAS # | CD126, Gene ID: 16194, Accession: NP_034689.2 |
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| Catalog # | MBS553305 |
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| Order / More Info | Mouse IL-6 Receptor Recombinant (IL-6R) from MYBIOSOURCE INC. |
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| Product Specific References | • anti-inflammatory effect of IL-6 receptor blockade on experimental corneal alkali burn .Invest. Ophthalmol. Vis. Sci., Mar 2012; 53: 4206. • exposure-response relationship of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in a large population of patients with rheumatoid arthritis .J. Clin. Pharmacol., Feb 2012; 10.1177/0091270012437585. • impact of IL-6 receptor inhibition on human memory b cells in vivo: impaired somatic hypermutation in preswitch memory b cells and m |
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