| 产品详情 |
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| Product Name | Recombinant Human Serine/threonine-protein kinase PAK 7 (PAK7), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 34.9kDa. Partial: 1-293aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7 |
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| Gene, Accession, CAS # | PAK7, UniProt: Q8TB93 |
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| Catalog # | RPC20702 |
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| Price | |
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| Order / More Info | Recombinant Human Serine/threonine-protein kinase PAK 7 (PAK7), partial from BIOMATIK |
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| Product Specific References | n/a |
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