| 产品详情 |
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| Antigenic Specificity | Annexin A5 (ANXA5) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Annexin V, also known as PAP-1 or Lipocortin V, is a ~30 kDa protein that binds to phospholipids in a calcium-dependent manner. All annexins contain a putative PKC binding site, but only annexin V has been identified as an inhibitor of this pathway. It may also signal, by direct interaction with VEGFR2 receptor, in the regulation of vascular endothelial cell proliferation. Annexin V preferentially binds phosphatidylserine, in competition with prothrombin, leading to inhibition of blood coagulation at sites of injury preceding contact between lipid components and coagulation factors that initiate thrombosis. The ability of Annexin V to bind specifically and robustly to phosphatidylserine makes it an attractive reagent in detecting apoptotic cells. Annexin V is inducible by glucocorticoids and can be phosphorylated by tyrosine and serine/threonine kinases. It is thought to block production of mediators of inflammation, such as prostaglandins and leukotrienes by inhibiting the release of arachidonic acid from membranes by phospholipase A2.Synonyms: ANX5, ENX2, PP4 |
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| Immunogen | Recombinant protein of human ANXA5 |
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| Other Names | anx|anx5|ANX V|anxa5|cb989|wu:fa98f06|wu:fj10f10|MGC89158|ANX5|ENX2|PP4|RPRGL3|Anx5|R74653|LC5|enx2 |
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| Gene, Accession # | Gene ID: 308,11747,25673 |
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| Catalog # | ABIN1512578 |
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| Price | |
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| Order / More Info | Annexin A5 (ANXA5) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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