产品名称 CD27 Molecule (CD27) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1111101
产品价格 现货询价,电话:010-67529703
产品规格 100 tests
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityCD27 Molecule (CD27)
CloneLT27
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
FormatPE-DyLight 594 conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FACS)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.
ImmunogenHuman peripheral blood lymphocytes
Other NamesTNFRSF7|S152|Tnfrsf7|Tp55|S152. LPFS2|T14
Gene, Accession #Gene ID: 939
Catalog #ABIN1111101
Price
Order / More InfoCD27 Molecule (CD27) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 17937677, 17526459, 9658722, 8241510
产品资料