产品详情 |
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Antigenic Specificity | Fatty Acid Amide Hydrolase (FAAH) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse . Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid . This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation . Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo . FAAH1 null mice also demonstrate an increased preference for alcohol and an increased voluntary uptake of alcohol as compared to wild-type mice, indicating a role of FAAH1 in modulating addictive behaviors . Synonyms: FAAH,FAAH1,MGC102823,MGC138146 , |
Immunogen | Recombinant protein of human FAAH |
Other Names | FAAH|faah|faah-1|Faxdc1|G630055L08Rik|FAAH-1|AW412498|AtFAAH|fatty acid amide hydrolase |
Gene, Accession # | Gene ID: 2166,338521,29347 |
Catalog # | ABIN1683575 |
Price | |
Order / More Info | Fatty Acid Amide Hydrolase (FAAH) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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