产品名称 PIG3 Antibody from ABBEXA
产品货号 abx030896
产品价格 现货询价,电话:010-67529703
产品规格 80 µl, 400 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityPIG3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl
Concentrationn/a
ApplicationsWB. RUO
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DescriptionThe protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3.
ImmunogenHuman PIG3.
Other NamesPIG3; Quinone oxidoreductase PIG3; Tumor protein p53-inducible protein 3; p53-induced gene 3 protein; TP53I3; Quinone oxidoreductase homolog
Gene, Accession #SwissProt: Q53FA7
Catalog #abx030896
Price
Order / More InfoPIG3 Antibody from ABBEXA
Product Specific Referencesn/a
产品资料