| 产品详情 |
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| Antigenic Specificity | Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (Extracellular Domain) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Defects in SLC1A3 are the cause of episodic ataxia type 6 (EA6). EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia.Subcellular location: Membrane, Multi-pass membrane protein.Tissue specificity: Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia. Also known as: Sodium-dependent glutamate/aspartate transporter 1, GLAST-1, Solute carrier family 1 member 3, SLC1A3, EAAT1, GLAST, GLAST1. |
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| Immunogen | A synthetic peptide from extracellular domain of human EAAT1 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with rat and mouse sequence. |
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| Other Names | AF001784|CG3747|Dglt-1|Dglut-1|Dmel\\CG3747|EAAT|EAAT1|dEAAT|dEAAT1|dEaat1|slc1a3|wu:fb98e05|wu:fd50b05|zgc:56661|zgc:77768|SLC1A3|GLAST|GluT-1|EA6|GLAST1|AI504299|B430115D02Rik|Eaat1|GLAST-1|GLU-T|Gmt1|MGluT1 |
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| Gene, Accession # | Gene ID: 6507 |
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| Catalog # | ABIN350309 |
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| Order / More Info | Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (Extracellular Domain) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 7521911, 18669648, 8123008, 8218410, 8647279 |
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