产品详情 |
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Antigenic Specificity | Solute Carrier Family 29 Member 3 (SLC29A3) (aa 2-50) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FUNCTION: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine. Defects in SLC29A3 are the cause of histiocytosis-lymphadenopathy plus syndrome (HLAS). SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Late endosome membrane. Lysosome membrane. Note: Observed in a punctate intracellular pattern showing partial colocalization with late endosomes/lysosomes. Not detected at the cell surface. Tissue specificity: Widely expressed in both adult and fetal tissues. Highest levels in placenta, uterus, ovary, spleen, lymph node and bone marrow. Lowest levels in brain and heart. Synonyms: Equilibrative nucleoside transporter 3, Solute carrier family 29 member 3, ENT3 |
Immunogen | A synthetic peptide from aa region 2-50 of human SLC29A3 conjugated to an immunogenic carrier protein was used as the antigen. |
Other Names | ENT3|HCLAP|HJCD|PHID|Ent3|4933435C21Rik|AW987637 |
Gene, Accession # | Gene ID: 55315 |
Catalog # | ABIN1842153 |
Price | |
Order / More Info | Solute Carrier Family 29 Member 3 (SLC29A3) (aa 2-50) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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