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| Product Name | Ataxin 3 (ATXN3) (AA 1-370) protein |
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| Description | Ataxin 3 is also known as Machado-Joseph disease protein 1. Machado-Joseph disease is one of several hereditary autosomal dominant neurodegenerative disorders. This protein contains trinucleotide CAG repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. Ataxin 3 interacts with the major histone acetyltransferases cAMP-response-element binding protein (CREB)-binding protein, p300, and p300/CREB-binding protein-associated factor and inhibits transcription by these coactivators. Also, ataxin-3 is a proteasome-associated factor that mediates the degradation of ubiquitinated proteins. Recombinant human Ataxin-3 was expressed in E. coli and purified by using conventional chromatography. Alternative Names: Machado-Joseph disease protein 1 homolog protein, Machado Joseph disease protein, AT3 protein, JOS protein, MJD1 protein, MJD gene protein, Machado Joseph disease protein 1 protein, EC 3.4.22. protein, ATXN3 protein, , Spinocerebellar ataxia type 3 protein protein, Rsca3 protein, MJD protein, Josephin protein, ATX3 protein, ATXN3 protein, SCA3 protein, Ataxin 3 protein, SCA3 gene protein |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | Mjd|zgc:56323|ATXN3|at3|jos|mjd|atx3|mjd1|sca3|ataxin-3|MJD1|MGC83584|AT3|ATX3|JOS|MJD|SCA3|2210008M02Rik|AI463012|AI647473|Sca3|Rsca3 |
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| Gene, Accession, CAS # | Gene ID: 4287 |
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| Catalog # | ABIN935045 |
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| Order / More Info | Ataxin 3 (ATXN3) (AA 1-370) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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