| 产品详情 |
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| Product Name | Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) peptide |
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| Description | MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | Prkmk2|CFC4|MAPKK2|MEK2|MKK2|PRKMK2|AA589381|MK2|ATMKK2|F27B13.50|F27B13_50|MAP KINASE KINASE 1|MAP kinase kinase 2|MK1 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN940180 |
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| Price | |
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| Order / More Info | Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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