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| Product Name | Recombinant Mouse Nogo-B receptor (Nus1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 13kDa. Cytoplasmic Domain: 24-120aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Di-trans,poly-cis-decaprenylcistransferaseCurated; Nogo-B receptorBy similarity; NgBRBy similarity; Nuclear undecaprenyl pyrophosphate synthase 1 homolog |
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| Gene, Accession, CAS # | Nus1, UniProt: Q99LJ8 |
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| Catalog # | RPC25510 |
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| Order / More Info | Recombinant Mouse Nogo-B receptor (Nus1), partial from BIOMATIK |
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| Product Specific References | n/a |
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