产品名称 Fibroblast Growth Factor 12 (FGF12) (Isoform 2), (AA 1-181) (Active) protein from ANTIBODIES-ONLINE GmbH
产品货号 ABIN2017805
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameFibroblast Growth Factor 12 (FGF12) (Isoform 2), (AA 1-181) (Active) protein
DescriptionFibroblast Growth Factor-12(FGF-12) is a heparin binding cytokine belonging to the FGF family. FGF-12 along with FGF-11, -13, and -14, form a sublineage within the FGF family: in contrast to the other members, they are all intracellular signaling proteins lacking signal peptides and containing a flanking domain beside the family conserved beta-trefoil domain. FGF-12 is expressed in the cartilaginous skeleton and heart, suggesting a role in the development of connective tissue and heart. In vivo, FGF-12 binds to Islet Brain-2 and Voltage-Gated Sodium Channels (VGSC), and plays a critical role in the membrane targeting and function of VGSC. FGF-12 has been implicated in heart diseases such as cardiac arrhythmias.Recombinant human Fibroblast Growth Factor-12 (rhFGF-12) produced in E. coli is a single non-glycosylated polypeptide chain containing 181 amino acids. A fully biologically active molecule, rhFGF-12 has a molecular mass of 20.4 kDa analyzed by reducing SDS-PAGE. Synonyms: FHF1, FGF12B
Size50 µg
Concentrationn/a
Applicationsn/a
Other NamesFHF1|FHF-1|MGC84150|FGF12|fgf12|zgc:153104|fhf1|fgf12b|DKFZp459P139|FGF12B|AV114868|FGF-12|Fhf1|Fhf1b
Gene, Accession, CAS #Gene ID: 2257
Catalog #ABIN2017805
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Order / More InfoFibroblast Growth Factor 12 (FGF12) (Isoform 2), (AA 1-181) (Active) protein from ANTIBODIES-ONLINE GmbH
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