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| Product Name | Fibroblast Growth Factor 12 (FGF12) (Isoform 2), (AA 1-181) (Active) protein |
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| Description | Fibroblast Growth Factor-12(FGF-12) is a heparin binding cytokine belonging to the FGF family. FGF-12 along with FGF-11, -13, and -14, form a sublineage within the FGF family: in contrast to the other members, they are all intracellular signaling proteins lacking signal peptides and containing a flanking domain beside the family conserved beta-trefoil domain. FGF-12 is expressed in the cartilaginous skeleton and heart, suggesting a role in the development of connective tissue and heart. In vivo, FGF-12 binds to Islet Brain-2 and Voltage-Gated Sodium Channels (VGSC), and plays a critical role in the membrane targeting and function of VGSC. FGF-12 has been implicated in heart diseases such as cardiac arrhythmias.Recombinant human Fibroblast Growth Factor-12 (rhFGF-12) produced in E. coli is a single non-glycosylated polypeptide chain containing 181 amino acids. A fully biologically active molecule, rhFGF-12 has a molecular mass of 20.4 kDa analyzed by reducing SDS-PAGE. Synonyms: FHF1, FGF12B |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FHF1|FHF-1|MGC84150|FGF12|fgf12|zgc:153104|fhf1|fgf12b|DKFZp459P139|FGF12B|AV114868|FGF-12|Fhf1|Fhf1b |
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| Gene, Accession, CAS # | Gene ID: 2257 |
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| Catalog # | ABIN2017804 |
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| Order / More Info | Fibroblast Growth Factor 12 (FGF12) (Isoform 2), (AA 1-181) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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