产品名称 ATG4C Antibody from ABBEXA
产品货号 abx030028
产品价格 现货询价,电话:010-67529703
产品规格 80 µl, 400 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityATG4C
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size80 µl, 400 µl
Concentrationn/a
ApplicationsWB, IHC. RUO
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionMacroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE) conjugated form, and has the capacity for the binding to autophagosomes. This ATG4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the C-terminal region of human ATG4C.
ImmunogenHuman ATG4C.
Other NamesAPG4 autophagy 4 homolog C; APG4-C; APG4C; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; autophagin-3; autophagy-related cysteine endopeptidase; autophagy-related cysteine endopeptidase 3; autophagy-related protein 4 homolog C; cysteine protease ATG4C; AUT; ATG4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); FLJ14867; AUT-like 1, cysteine endopeptidase; OTTHUMP00000010715; autophagy-related cystei
Gene, Accession #Accession: NP_116241.2, NP_835739.1, SwissProt: Q96DT6
Catalog #abx030028
Price
Order / More InfoATG4C Antibody from ABBEXA
Product Specific Referencesn/a
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