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| Product Name | phosphorylase, Glycogen, Brain (GPBB) protein |
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| Description | Glycogen phosphorylase is one of the phosphorylaseenzymes(EC2.4.1.1). It breaks up glycogeninto glucosesubunits. Glycogenis left with one less glucosemolecule, and the free glucosemolecule is in the form of glucose-1-phosphate. In order to be used for metabolism, it must be converted to glucose-6-phosphateby the enzyme phosphoglucomutase.Glycogen phosphorylase can only act on linearchainsof glycogen(a 1-4 glycosidic linkage). Its work will immediately come to a halt four residues away from a 1-6 branch(which are exceedingly common in glycogen). In these situations, a debranching enzymeis necessary, which will straighten out the chain in that area. Additionally, an alpha 1-6 glucosidaseenzymeis required to break the remaining 1-6 residue that remains in the new linear chain. After all this is done, glycogen phosphorylase can continue.An insulinstimulated enzyme known as phosphoprotein phosphatase(PP-1) inactivates glycogen phosphorylase to prevent glycogen break up.GPBB - a sensitive marker for the AMI diagnosis within 4 hours after the onset of chest pain. It has also been shown that GPBB is increased in a considerable proportion of AMI patients within 2-3 hours from chest pain onset. GPBB is increased early in patients with unstable angina. GPBB can also be a sensitive marker for the detection of peri-operative myocardial ischaemia and infarction in patients undergoing coronary artery bypass grafting Synonyms: Glycogen phosphorylase brain form, EC 2.4.1.1, GPBB, MGC9213, PYGB |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | Immunoassay (IA),Transfected Cell Culture (TCC) |
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| Other Names | pygb|GPBB|GLYPHOA |
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| Gene, Accession, CAS # | Gene ID: 5834 |
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| Catalog # | ABIN805433 |
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| Order / More Info | phosphorylase, Glycogen, Brain (GPBB) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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