产品名称 CD105 (Endoglin / TGF-Beta1/3 Receptor) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH
产品货号 ABIN804341
产品价格 现货询价,电话:010-67529703
产品规格 2 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameCD105 (Endoglin / TGF-Beta1/3 Receptor) (Active) protein (His tag)
DescriptionEndoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex.The protein consists of a homodimer of 180 kDa with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. Beside TGF-beta signaling endoglin may have other functions. It has been postulated that endoglin is involved in the cytoskeletal organization affecting cell morphology and migration. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development . Experimental mice without the endoglin gene die due to cardiovascular abnormalities Synonyms: CD105, ENG, END, ORW, HHT1, ORW1, FLJ41744, Endoglin
Size2 µg
Concentrationn/a
Applicationsn/a
Other NamesEND|HHT1|ORW1|AI528660|AI662476|CD105|S-endoglin
Gene, Accession, CAS #Gene ID: 2022
Catalog #ABIN804341
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Order / More InfoCD105 (Endoglin / TGF-Beta1/3 Receptor) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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