| 产品详情 |
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| Antigenic Specificity | GPCR GPR7/NPBWR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug |
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| Concentration | 500ug/ml. |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Neuropeptides B/W receptor 1, also known as NPBW1 and GPR7, is a human protein encoded by the NPBWR1 gene. In rodent models, NPBWR1 is over-expressed in Schwann cells associated with neuropathic pain, suggesting it inhibits inflammatory pain responses. Mice without NPBW1 exhibited a stronger hostile reaction to intruders, suggesting NPBW1 has a role in stress responses. Early studies indicated that NPB and NPW had a complex effect on appetite, but generally led to anorexia. Similarly, male rats lacking NPBWR1 exhibited hyperphagiaand adult-onset obesity, though why female rats are unaffected is unknown. Researchers speculated that activating these pathways might decrease obesity, and synthesized a small-molecule ligand that is capable of stimulating both receptors at low concentrations. |
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| Immunogen | E.coli-derived human GPCR GPR7/NPBWR1 recombinant protein (Position: V58-A328). |
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| Other Names | Neuropeptides B/W receptor type 1; G-protein coupled receptor 7; NPBWR1; GPR7 |
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| Gene, Accession # | NPBWR1, UniProt: P48145 |
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| Catalog # | A08247-1 |
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| Price | |
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| Order / More Info | GPCR GPR7/NPBWR1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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