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| Product Name | MreB Perturbing Compound A22 |
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| Description | Purity >95%. MreB is an actin-like protein expressed in bacteria. It determines the rod shape of cells and has critical roles in cell division, chromosome segregation, and cell polarity. MreB perturbing compound A22 is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. It blocks normal rod shape formation and inhibits chromosome partitioning in E. coli, inhibiting growth (MIC = 3.1 µg/ml). It interferes with chromosome segregation in C. crescentus by preventing MreB binding to chromosomes. In V. cholerae, A22 prevents the development of normal cell shape and alters nucleoid morphology. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | carbamimidothioic acid,(3,4-dichlorophenyl)methyl ester, monohydrochloride |
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| Gene, Accession, CAS # | CAS: 22816-60-0 |
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| Catalog # | LS-H8812 |
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| Order / More Info | MreB Perturbing Compound A22 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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