| 产品详情 |
| Edit |   |
|---|
| Product Name | WM1985 Viable Cells (1 x10^6 cells) |
|---|
| Description | WM1985 is a human melanoma cell line that displays flat cell morphology and forms tight colonies in culture medium. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including homozygous deletion, and is wild type for N-RAS, c-KIT, and CDK4. WM1985 cells produce xenograft tumors when injected into immunocompromised mice. |
|---|
| Size | 1 mL |
|---|
| Concentration | 1x10^6 |
|---|
| Applications | The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. |
|---|
| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | WM1985-01-0001 |
|---|
| Price | |
|---|
| Order / More Info | WM1985 Viable Cells (1 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|