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| Product Name | WM1852 Viable Cells (1 x10^6 cells) |
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| Description | WM1852 is a metastatic human melanoma cell line that displays mesenchymal and spherical morphology. These cells require 10% FBS to adhere to culture dish. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM1852 cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 1 mL |
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| Concentration | 1x10^6 |
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| Applications | The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM1852-01-0001 |
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| Price | |
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| Order / More Info | WM1852 Viable Cells (1 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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