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| Product Name | WM9 Purified Genomic DNA |
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| Description | DNA was prepared from cell line WM9. WM9 is a human metastatic melanoma cell line that was established from a metastatic site (left axillary node) in a male patient. This cell line features the V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN hemizygous deletion, and is wild type for N-RAS, c-KIT, and CDK4. WM9 cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 5 µg |
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| Concentration | 200 ng / µl |
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| Applications | Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM9-02-0200 |
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| Order / More Info | WM9 Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Dorothee Herlyn et al., In Vitro Properties of Human Melanoma Cells Metastatic in Nude Mice. Cancer Research (1990) v50 2296-2302. |
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