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| Product Name | WM873-1 Purified Genomic DNA |
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| Description | DNA was prepared from cell line WM873-1. WM873-1 is a metastatic human melanoma cell line. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line expresses PTEN loss of function including hemizygous deletion, and is wild type for N-RAS, c-KIT, and CDK4 genes. WM873-1 cells match with WM858 and WM873-2. These cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 5 µg |
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| Concentration | 200ng/µL |
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| Applications | Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM873-1-02-0200 |
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| Order / More Info | WM873-1 Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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