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| Product Name | WM3854 Purified Genomic DNA |
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| Description | DNA was prepared from cell line WM3854. WM3854 is a human metastatic melanoma cell line that displays a mesenchymal morphology. This cell line was established from a heavily pigmented metastatic site (right upper flank of back) in a 64-year-old male with superficial and deep inguinal nodes forming a 3.0 cm mass. This cell line contains a Q61L mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation. This cell line is known to be wild type for BRAF, c-KIT and CDK4. WM3854 cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 25 µg |
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| Concentration | 200 ng / µl |
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| Applications | Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM3854-02-5000 |
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| Order / More Info | WM3854 Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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