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| Product Name | WM1341D Purified Genomic DNA |
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| Description | DNA was prepared from cell line WM1341D. WM1341D is a tumorigenic (VGP) primary melanoma cell line with competence for metastasis. These cells display epithelial square and triangular morphology in culture. This cell line features the specific V600R (Val600Arg) mutation at codon 600 in the BRAF gene. The V600R mutation results in an amino acid substitution at position 600 in BRAF, from a valine (V) to an arginine (R). This mutation occurs within the activation segment of the kinase domain. Mutations at V600 result in increased kinase activity and are transforming in vitro. WM1341D cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 25 µg |
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| Concentration | 200 ng / µl |
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| Applications | Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM1341D-02-5000 |
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| Order / More Info | WM1341D Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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